Single cell sorting identifies progenitor cell population from full thickness bovine articular cartilage
نویسندگان
چکیده
منابع مشابه
Mesenchymal Stem Cell Purification from the Articular Cartilage Cell Culture
Objective Articular cartilage as an avascular skeletal tissue possesses limited capacity to heal. On the other hand, it is believed that the regeneration capacity of each tissue is largely related to its stem cell contents. Little is known about the presence of mesenchymal stem cells in articular cartilage tissue. This subject is investigated in the present study. Materials and Methods Artic...
متن کاملThe surface of articular cartilage contains a progenitor cell population.
It is becoming increasingly apparent that articular cartilage growth is achieved by apposition from the articular surface. For such a mechanism to occur, a population of stem/progenitor cells must reside within the articular cartilage to provide transit amplifying progeny for growth. Here, we report on the isolation of an articular cartilage progenitor cell from the surface zone of articular ca...
متن کاملmesenchymal stem cell purification from the articular cartilage cell culture
objective articular cartilage as an avascular skeletal tissue possesses limited capacity to heal. on the other hand, it is believed that the regeneration capacity of each tissue is largely related to its stem cell contents. little is known about the presence of mesenchymal stem cells in articular cartilage tissue. this subject is investigated in the present study. materials and methods articula...
متن کاملStudy of Differentiation Potential of the Dedifferentiated Chondrocytes From Rat Articular Cartilage into Skeletal Cell Lineages
Purpose: Dedifferentiation of the chondrocyte from rat articular cartilage with multiple subcultures and study of the redifferentiation potential of the cells into bone, cartilage and fat cell lineages. Materials and Methods: In this experimental study, chondrocytes from rat articular cartilage were isolated and expanded through several successive subcultures during which the expression levels ...
متن کاملIdentification and Clonal Characterisation of a Progenitor Cell Sub-Population in Normal Human Articular Cartilage
BACKGROUND Articular cartilage displays a poor repair capacity. The aim of cell-based therapies for cartilage defects is to repair damaged joint surfaces with a functional replacement tissue. Currently, chondrocytes removed from a healthy region of the cartilage are used but they are unable to retain their phenotype in expanded culture. The resulting repair tissue is fibrocartilaginous rather t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2014
ISSN: 1063-4584
DOI: 10.1016/j.joca.2014.07.002